Yes, this is possible. I generally create a single mapping file with all the repeating data mapped in it - but if you want, you can also create separate mapping files and data connections in your form, and use multiple SubmitToSharePointList commands, specifying the mapping parameter, like:
SubmitToSharePointList /submit=WSSubmit /mapping=mappingA
SubmitToSharePointList /submit=WSSubmit /mapping=mapping
And so on.