Okay - the couple of people who need to enter data - are they all using the same machine? Different machines, but on the same network? If everyone is on the same network, you could probably put your Access DB on a network share that everyone has access to, create an InfoPath form off the database, and publish the form to the same location. However - if you take this approach, they'd need to at least have an intranet connection. If everyone is using the same computer, then you could just have the DB and form locally on that computer - in a folder that all users can access.
EDITED: To clarify, upon re-reading - yes, you can put the DB on a computer and have an IP form on the same computer that connects to that DB - and base the form off the DB.