Hi Smaur,
As long as the Access DB is in the same domain, you should be able to use some form of Windows Auth to get at it. InfoPath will popup auth dialogs for you to fill in when you access a machine outside of your domain. I'm not sure exactly how Access authenticates, though.
You can make the form full trust to access the Access DB, but this will limit deployment options (since you'll have to sign the form or deploy an msi).
The other thing you could do is to write some code to grab the user names and authenticate them but the form would likely have to be full trust here too because users would be authenticating.
A third option is to build a web service in your domain on top of the Access DB and access that using Windows Authentication.
Some random ideas... I'm not very confident that they will help you, but figured I'd respond anyway ...
Patrick Halstead [InfoPath MVP]
InfoPathDev
Patrick Halstead
Project Manager at Qdabra